TJP1 Antikörper

Produktnummer ABIN2192206

Produktdetails anti-TJP1 Antikörper

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TJP1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Applikationshinweise: For immunfluorescence and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50..

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen für anti-TJP1 Antikörper (ABIN2192206)

Balda, Anderson: "Two classes of tight junctions are revealed by ZO-1 isoforms." in: The American journal of physiology, Vol. 264, Issue 4 Pt 1, pp. C918-24, (1993) (PubMed).

Details zu TJP1

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Andere Bezeichnung: Zona Occludens 1 (TJP1 Produkte)

Synonyme: ZO-1 antikoerper, ZO1 antikoerper, zo1 antikoerper, tight junction protein 1 antikoerper, tight junction protein ZO-1 antikoerper, TJP1 antikoerper, Tjp1 antikoerper, LOC396567 antikoerper

Hintergrund: The polyclonal antibody recognizes human zona occludens 1 (ZO-1), an ~220 kDa tight junction protein belonging to the membrane-associated guanlyate kinase (MAGUK) family. Members of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain- containing proteins, like ZO-1, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling complexes often at the sites of cell-cell contact. The effectiveness and

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization