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SCGB1A1 Antikörper (Secretoglobin, Family 1A, Member 1 (Uteroglobin)) Primary Antibody

SCGB1A1 Reaktivität: Human IA, IHC (fro), IHC (p), WB Wirt: Maus Monoclonal AY1E6 unconjugated
Pubmed (1 reference)
Produktnummer ABIN2192038
$659.59
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle SCGB1A1 Antikörper anzeigen
    SCGB1A1
    Reaktivität
    • 54
    • 48
    • 23
    Human
    Wirt
    • 86
    • 8
    • 1
    • 1
    Maus
    Klonalität
    • 78
    • 17
    Monoklonal
    Konjugat
    • 35
    • 14
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SCGB1A1 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 36
    • 27
    • 26
    • 24
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Sterilität
    0.2 μm filtered
    Klon
    AY1E6
  • Applikationshinweise
    For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Geerts, Jorens, Willems, De Ley, Slegers: "Natural inhibitors of neutrophil function in acute respiratory distress syndrome." in: Critical care medicine, Vol. 29, Issue 10, pp. 1920-4, (2001) (PubMed).

  • Target
    SCGB1A1
    Andere Bezeichnung
    Clara Cell Protein (SCGB1A1 Produkte)
    Synonyme
    CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1, UGL, PCB-BP, UG, Utg, PCBB, Ugb, SCGB1A1, secretoglobin family 1A member 1, secretoglobin, family 1A, member 1 (uteroglobin), urinary protein 2, SCGB1A1, Scgb1a1, Rup2
    Hintergrund
    The monoclonal antibody AY1E6 recognizes the anti-inflammatory mediator Clara cell protein (CC16). Clara cell protein or urinary protein 1 is a homodimeric protein of 16 kD and is secreted predominantly by Clara cells in terminal bronchioles and from puberty on in the male urogenital tract. CC16 is formed by two chains, each with a molecular weight of 7.9 kD. CC16 occurs in very high concentrations in respiratory tract derived fluids such as sputum or bronchoalveolar lavage fluid. CC16 occurs also in urogenital secretions, such as amniotic fluid, urine and semen. The protein difusses passively into serum. CC16 behaves like an anti-cytokine by downregulating the production of IFN-gamma, IL-1 and TNF-alpha by stimulated leukocytes. Besides this, CC16 reduces the antiviral activity and the augmentation of phagocytosis induced by IFN-gamma.
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