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CXCL10 Antikörper (Chemokine (C-X-C Motif) Ligand 10) (FITC) Primary Antibody

CXCL10 Reaktivität: Human IA, IHC (fro), FACS, WB Wirt: Maus Monoclonal 6D4 FITC
Pubmed (3 Referenzen)
Produktnummer ABIN2191896
$518.25
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle CXCL10 Antikörper anzeigen
    CXCL10
    Reaktivität
    • 101
    • 38
    • 27
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 98
    • 35
    • 5
    • 4
    • 2
    • 1
    Maus
    Klonalität
    • 101
    • 43
    Monoklonal
    Konjugat
    • 74
    • 30
    • 13
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CXCL10 Antikörper ist konjugiert mit FITC
    Applikation
    • 100
    • 74
    • 38
    • 27
    • 14
    • 14
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Western Blotting (WB)
    Sterilität
    0.2 μm filtered
    Klon
    6D4
  • Applikationshinweise
    For immunohistochemistry, flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Acitvated plasmacytoid dendritic cells control Negative Normal liver control 1
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 1.0 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Curbishley, Eksteen, Gladue, Lalor, Adams: "CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow." in: The American journal of pathology, Vol. 167, Issue 3, pp. 887-99, (2005) (PubMed).

    Giustizieri, Albanesi, Scarponi, De Pità, Girolomoni: "Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo." in: The American journal of pathology, Vol. 161, Issue 4, pp. 1409-18, (2002) (PubMed).

    Hamamdzic, Phillips-Dorsett, Altman-Hamamdzic, London, London: "Reovirus triggers cell type-specific proinflammatory responses dependent on the autocrine action of IFN-beta." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 280, Issue 1, pp. L18-29, (2001) (PubMed).

  • Target
    CXCL10
    Andere Bezeichnung
    C-X-C Motif Chemokine 10 (CXCL10 Produkte)
    Synonyme
    CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, CRG-2, IP10, Ifi10, Scyb10, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10, chemokine (C-X-C motif) ligand 10, CXCL10, cxl10, Cxcl10
    Hintergrund
    The monoclonal antibody 6D4 recognizes human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids. IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFNγ inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation. Aliases 10 kDa interferon gamma-induced protein, CXCL10, Small-inducible cytokine B10 Immunogen Recombinant human IP-10
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