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LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) Antikörper (FITC)

LIMK1/2 Reaktivität: Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN2177323
  • Target Alle LIM Domain Kinase 1/2 (LIMK1/2) Antikörper anzeigen
    LIM Domain Kinase 1/2 (LIMK1/2)
    Bindungsspezifität
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    pThr505
    Reaktivität
    • 21
    • 8
    • 6
    • 3
    • 3
    • 1
    Ratte
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    FITC
    Applikation
    • 22
    • 12
    • 12
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    LIM Domain Kinase 1/2 (LIMK1/2)
    Andere Bezeichnung
    LIMK1LIMK2 (LIMK1/2 Produkte)
    Synonyme
    LIMK antikoerper, LIM domain kinase 2 antikoerper, LIMK2 antikoerper
    Hintergrund

    Synonyms: LIMK1Thr508, EC 2.7.11.1, LIM domain kinase 1, LIM mot-containing protein kinase, LIMK, LIMK-1, LIMK2, LIMK-2, LIM domain kinase 2, LIMK1_HUMAN.

    Background: LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development, it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.

    Gen-ID
    3984
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