HPV16 E7 Antikörper (Middle Region) (Biotin)
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- Target Alle HPV16 E7 (HPV-16 E7) Antikörper anzeigen
- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human Papillomavirus 16 (HPV-16)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HPV16 E7 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody may also detect HPV35-E7
- Kreuzreaktivität
- Human, Virus
- Kreuzreaktivität (Details)
- HPV16
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from middle of HPV16-E7
- Isotyp
- IgG
- Top Product
- Discover our top product HPV-16 E7 Primärantikörper
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- Applikationshinweise
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WB 1:100-1000
IHC-P 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
- Abstract
- HPV-16 E7 Produkte
- Synonyme
- transforming protein E7 antikoerper, E7 antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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Synonyms: Protein E7, E7
Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.
- Gen-ID
- 1489079
- UniProt
- P03129
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