USP11 Antikörper (Ubiquitin Specific Peptidase 11) (AA 32-300)

Details for Product anti-USP11 Antibody No. ABIN1944797, Anbieter: Anmelden zum Anzeigen
Antigen
  • USP11
  • DKFZp459L098
  • UHX1
  • 6230415D12Rik
  • mKIAA4085
  • Uhx1
  • ubiquitin specific peptidase 11
  • universal stress protein
  • USP11
  • RR_RS19935
  • Usp11
Epitop
AA 32-300, C-Term
29
14
11
7
7
6
4
2
2
2
1
1
1
1
1
Reaktivität
Human
90
15
12
3
1
Wirt
Maus
65
17
10
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser USP11 Antikörper ist unkonjugiert
5
5
5
5
5
5
Applikation
Western Blotting (WB)
79
57
41
8
7
7
5
4
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 AA from the C-terminal region of human USP11.
Klon 1220CT620-193-189
Isotyp IgG1
Reinigung This antibody is purified through a protein G column, followed by dialysis against PBS.
Plasmids, Primers & others Plasmide, Primers & weitere USP11 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung USP11 (USP11 Antibody Abstract)
Hintergrund Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
Synonyms: Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11, USP11, UHX1
Molekulargewicht 109817 Da
Gen-ID 8237
UniProt P51784
Applikations-hinweise WB - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Bilder des Herstellers
Western Blotting (WB) image for anti-Ubiquitin Specific Peptidase 11 (USP11) (AA 32-300), (C-Term) antibody (ABIN1944797) anti-Ubiquitin Specific Peptidase 11 (USP11) (AA 32-300), (C-Term) antibody
Produkt verwendet in: Yamaguchi, Kimura, Miki, Yoshida: "The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha)." in: The Journal of biological chemistry, Vol. 282, Issue 47, pp. 33943-8, 2007 (PubMed).

Schoenfeld, Apgar, Dolios, Wang, Aaronson: "BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage." in: Molecular and cellular biology, Vol. 24, Issue 17, pp. 7444-55, 2004 (PubMed).

Ideguchi, Ueda, Tanaka, Yang, Tsuji, Ohno, Hagiwara, Aoki, Ishigatsubo: "Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM." in: The Biochemical journal, Vol. 367, Issue Pt 1, pp. 87-95, 2002 (PubMed).

Swanson, Freund, Ploder, McInnes, Valle: "A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders." in: Human molecular genetics, Vol. 5, Issue 4, pp. 533-8, 1996 (PubMed).

Allgemeine Veröffentlichungen Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

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