FCGR3B Antikörper (N-Term)

Produktnummer ABIN1944735

Produktdetails anti-FCGR3B Antikörper

Target: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Bindungsspezifität: AA 12-47, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FCGR3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FCGR3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-47 amino acids from the N-terminal region of human FCGR3B.

Klon: RB47719

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-FCGR3B Antikörper (ABIN1944735)

Ravetch, Perussia: "Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions." in: The Journal of experimental medicine, Vol. 170, Issue 2, pp. 481-97, (1989) (PubMed).

Peltz, Grundy, Lebo, Yssel, Barsh, Moore: "Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 3, pp. 1013-7, (1989) (PubMed).

Scallon, Scigliano, Freedman, Miedel, Pan, Unkeless, Kochan: "A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 5079-83, (1989) (PubMed).

Simmons, Seed: "The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein." in: Nature, Vol. 333, Issue 6173, pp. 568-70, (1988) (PubMed).

Details zu FCGR3B

Target: FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))

Andere Bezeichnung: FCGR3B (FCGR3B Produkte)

Synonyme: CD16 antikoerper, CD16b antikoerper, FCG3 antikoerper, FCGR3 antikoerper, FCR-10 antikoerper, FCRIII antikoerper, FCRIIIb antikoerper, FcRIII antikoerper, Fc fragment of IgG receptor IIIb antikoerper, Fc receptor, IgG, low affinity III antikoerper, Fc fragment of IgG receptor IIIa antikoerper, Fc-gamma RIII antikoerper, FCGR3B antikoerper, Fcgr3 antikoerper, FCGR3A antikoerper, FCGR3 antikoerper

Hintergrund: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Molekulargewicht: 26216

Gen-ID: 2215

UniProt: O75015