INSM1 Antikörper (N-Term)

Produktnummer ABIN1888097

Produktdetails anti-INSM1 Antikörper

Target: INSM1 (Insulinoma-Associated 1 (INSM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide from near the amino terminus of human IA-1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu INSM1

Target: INSM1 (Insulinoma-Associated 1 (INSM1))

Andere Bezeichnung: IA-1 (INSM1 Produkte)

Synonyme: IA-1 antikoerper, IA1 antikoerper, INSM-1 antikoerper, Insm1 antikoerper, fc13a09 antikoerper, wu:fc13a09 antikoerper, zINSM-1 antikoerper, zgc:63866 antikoerper, INSM1 antikoerper, ia-1 antikoerper, zgc:77257 antikoerper, INSM transcriptional repressor 1 antikoerper, insulinoma-associated 1 antikoerper, insulinoma-associated 1b antikoerper, insulinoma associated 1 antikoerper, insulinoma associated 1 L homeolog antikoerper, insulinoma-associated 1a antikoerper, INSM1 antikoerper, Insm1 antikoerper, insm1b antikoerper, insm1 antikoerper, insm1.L antikoerper, insm1a antikoerper

Hintergrund: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system.Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb.It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation.IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.
Synonyms: Insulinoma-associated 1, INSM1, IA1

NCBI Accession: NP_002187