SLC39A1 Antikörper (N-Term)

Produktnummer ABIN1888014

Produktdetails anti-SLC39A1 Antikörper

Target: SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of human ZIP1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SLC39A1

Target: SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))

Andere Bezeichnung: ZIP1 (SLC39A1 Produkte)

Synonyme: cb629 antikoerper, DrZIP1 antikoerper, sb:cb629 antikoerper, zgc:111852 antikoerper, frzip1p antikoerper, zip1 antikoerper, zirtl antikoerper, ZIP1 antikoerper, ZIRTL antikoerper, Zip1 antikoerper, Zirtl antikoerper, solute carrier family 39 (zinc transporter), member 1 antikoerper, solute carrier family 39 member 1 antikoerper, solute carrier family 39 member 1 L homeolog antikoerper, slc39a1 antikoerper, Slc39a1 antikoerper, SLC39A1 antikoerper, slc39a1.L antikoerper

Hintergrund: ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer.More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappaB, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
Synonyms: Solute carrier family 39 member A1, Slc39A1, ZIRTL

NCBI Accession: NP_055252

Pathways: Autophagie