ARHGEF17 Antikörper (Center)

Produktnummer ABIN1887696

Produktdetails anti-ARHGEF17 Antikörper

Target: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF17 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the center of human TEM4.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ARHGEF17

Target: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Andere Bezeichnung: TEM4 (ARHGEF17 Produkte)

Synonyme: P164RHOGEF antikoerper, TEM4 antikoerper, p164-RhoGEF antikoerper, 8030463K16 antikoerper, AI428794 antikoerper, AW558066 antikoerper, BC035332 antikoerper, mKIAA0337 antikoerper, Rho guanine nucleotide exchange factor 17 antikoerper, Rho guanine nucleotide exchange factor (GEF) 17 antikoerper, ARHGEF17 antikoerper, Arhgef17 antikoerper

Hintergrund: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions.TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain.TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart.It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation.Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues.TEM4 could also prove to be useful targets therapeutically.
Synonyms: Tumor endothelial marker 4, ARHGEF17, Rho guanine nucleotide exchange factor 17, p164RHOGEF

UniProt: Q96PE2