SLC39A3 Antikörper (Center)

Produktnummer ABIN1887630

Produktdetails anti-SLC39A3 Antikörper

Target: SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human ZIP3.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SLC39A3

Target: SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))

Andere Bezeichnung: ZIP3 (SLC39A3 Produkte)

Synonyme: AI845814 antikoerper, Zip3 antikoerper, ZIP3 antikoerper, wu:fc84e09 antikoerper, zgc:158334 antikoerper, solute carrier family 39 (zinc transporter), member 3 antikoerper, solute carrier family 39 member 3 antikoerper, Slc39a3 antikoerper, slc39a3 antikoerper, SLC39A3 antikoerper

Hintergrund: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice.Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient.More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
Synonyms: Solute carrier family 39 member A3, Slc39A3

NCBI Accession: NP_653165

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie