PKDCC Antikörper (Center)

Produktnummer ABIN1887552

Produktdetails anti-PKDCC Antikörper

Target: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKDCC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the center of human VLK.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PKDCC

Target: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Andere Bezeichnung: VLK (PKDCC Produkte)

Hintergrund: VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm.It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups.VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme.It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi.Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality.It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
Synonyms: Vertebrate lonesome kinase, protein kinase domain containing cytoplasmic homolog, PKDCC, SGK439