TLR11 Antikörper (C-Term)

Produktnummer ABIN1887382

Produktdetails anti-TLR11 Antikörper

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Ion exchange chromatography purified

Immunogen: Peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Andere Bezeichnung: TLR11 (Tlr11 Produkte)

Synonyme: RGD1564460 antikoerper, Gm287 antikoerper, toll-like receptor 11 antikoerper, Tlr11 antikoerper

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors.TLR11 is one of three mouse TLRs that lack a human ortholog.It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

NCBI Accession: NP_991388

Pathways: Activation of Innate immune Response