TCP1 alpha/CCTA Antikörper (AA 357-630)

Produktnummer ABIN1886403

Dieses Anti-TCP1 alpha/CCTA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TCP1 alpha/CCTA in WB und IF. Geeignet für Human.

Kurzübersicht für TCP1 alpha/CCTA Antikörper (AA 357-630) (ABIN1886403)

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCP1 alpha/CCTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-TCP1 alpha/CCTA Antikörper

Bindungsspezifität: AA 357-630

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 357 and 630 of p63

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu TCP1 alpha/CCTA

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Andere Bezeichnung: p63

Hintergrund: This gene encodes a member of the p53 family of transcription factors.An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues.p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8.Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins.Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.[provided by RefSeq]

Molekulargewicht: 77 kDa

Gen-ID: 8626

NCBI Accession: NP_003713, NM_003722