TBP Antikörper

Produktnummer ABIN1882282

Produktdetails anti-TBP Antikörper

Target: TBP (TATA Box Binding Protein (TBP))

Reaktivität: Human, Maus, Ratte, Cynomolgus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: Purified His-tagged TBP protein was used to produced this monoclonal antibody.

Klon: 830CT4-3-3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TBP Antikörper (ABIN1882282)

Hoffman, Sinn, Yamamoto, Wang, Roy, Horikoshi, Roeder: "Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)." in: Nature, Vol. 346, Issue 6282, pp. 387-90, (1990) (PubMed).

Peterson, Tanese, Pugh, Tjian: "Functional domains and upstream activation properties of cloned human TATA binding protein." in: Science (New York, N.Y.), Vol. 248, Issue 4963, pp. 1625-30, (1990) (PubMed).

Kao, Lieberman, Schmidt, Zhou, Pei, Berk: "Cloning of a transcriptionally active human TATA binding factor." in: Science (New York, N.Y.), Vol. 248, Issue 4963, pp. 1646-50, (1990) (PubMed).

Details zu TBP

Target: TBP (TATA Box Binding Protein (TBP))

Andere Bezeichnung: TBP (TBP Produkte)

Synonyme: GTF2D antikoerper, GTF2D1 antikoerper, HDL4 antikoerper, SCA17 antikoerper, TFIID antikoerper, Gtf2d antikoerper, fd20h06 antikoerper, si:zc101n13.2 antikoerper, wu:fd20h06 antikoerper, zgc:66213 antikoerper, TBP1 antikoerper, TBP antikoerper, tbp antikoerper, CG9874 antikoerper, Dmel\\CG9874 antikoerper, RBP antikoerper, TBP38 antikoerper, TFIIDtau antikoerper, TfIID antikoerper, dTBP antikoerper, dTFIID antikoerper, dTbp antikoerper, dtbp antikoerper, gtf2d antikoerper, gtf2d1 antikoerper, sca17 antikoerper, tfiid antikoerper, tfiidtau antikoerper, xtbp antikoerper, tbp-a antikoerper, tbp-b antikoerper, TATA-box binding protein antikoerper, TATA box binding protein antikoerper, TATA binding protein antikoerper, TATA-box binding protein L homeolog antikoerper, TATA-box-binding protein antikoerper, TATA-box binding protein S homeolog antikoerper, TBP antikoerper, Tbp antikoerper, tbp antikoerper, tbp.L antikoerper, tbp.S antikoerper

Hintergrund: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Molekulargewicht: 37698

NCBI Accession: NP_001165556, NP_003185

UniProt: P20226

Pathways: WNT Signalweg