SUMO2 Antikörper

Produktnummer ABIN1882280

Produktdetails anti-SUMO2 Antikörper

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SUMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Homologie: B, C, Ha, Pr, M, Pig

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.

Klon: 973CT8-1-1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SUMO2 Antikörper (ABIN1882280)

Xu, Au: "Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1." in: The Biochemical journal, Vol. 386, Issue Pt 2, pp. 325-30, (2005) (PubMed).

Reverter, Lima: "A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex." in: Structure (London, England : 1993), Vol. 12, Issue 8, pp. 1519-31, (2004) (PubMed).

Mannen, Tseng, Cho, Li: "Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene." in: Biochemical and biophysical research communications, Vol. 222, Issue 1, pp. 178-80, (1996) (PubMed).

Details zu SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Andere Bezeichnung: SUMO2 (SUMO2 Produkte)

Synonyme: HSMT3 antikoerper, SMT3B antikoerper, SMT3H2 antikoerper, SUMO3 antikoerper, Smt3A antikoerper, SMT3A antikoerper, SMT3H1 antikoerper, SUMO-3 antikoerper, Smt3B antikoerper, Smt3h2 antikoerper, sumo2 antikoerper, zgc:92241 antikoerper, SUMO2 antikoerper, SUMO-2 antikoerper, Smt3b antikoerper, hsmt3 antikoerper, smt3b antikoerper, smt3h2 antikoerper, sumo-2 antikoerper, PSMT3 antikoerper, ATSUMO2 antikoerper, MCO15.11 antikoerper, MCO15_11 antikoerper, SMALL UBIQUITIN-LIKE MODIFIER 2 antikoerper, SUM2 antikoerper, SUMO 2 antikoerper, small ubiquitin-like modifier 2 antikoerper, small ubiquitin-like modifier 2 antikoerper, small ubiquitin-like modifier 3 antikoerper, small ubiquitin-like modifier 2b antikoerper, small ubiquitin-related modifier 2 antikoerper, small ubiquitin-like modifier 2 S homeolog antikoerper, small ubiquitin-like modifier 2 L homeolog antikoerper, SUMO2 antikoerper, SUMO3 antikoerper, Sumo2 antikoerper, sumo2b antikoerper, LOC714892 antikoerper, sumo2.S antikoerper, sumo2.L antikoerper

Hintergrund: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

Molekulargewicht: 10871

NCBI Accession: NP_001005849, NP_008868

UniProt: P61956

Pathways: Methionine Biosynthetic Process