SOX2 Antikörper (SRY (Sex Determining Region Y)-Box 2)

Details for Product anti-SOX2 Antibody No. ABIN1882277, Anbieter: Anmelden zum Anzeigen
Antigen
  • ANOP3
  • MCOPS3
  • RGD1565646
  • Sox-2
  • lcc
  • ysb
  • cb236
  • wu:fb83g04
  • wu:fc14d07
  • zgc:65860
  • zgc:77389
  • SRY-box2
  • Xsox-2
  • anop3
  • mcops3
  • sox-2
  • SRY-box 2
  • SRY box 2
  • SRY (sex determining region Y)-box 2
  • SRY-box 2 S homeolog
  • SOX2
  • Sox2
  • sox2
  • sox2.S
Reaktivität
Human
443
163
84
32
28
20
15
15
13
12
10
9
9
6
5
4
4
3
2
2
1
1
1
1
1
Wirt
Maus
280
171
6
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser SOX2 Antikörper ist unkonjugiert
21
19
19
16
15
11
9
9
8
8
5
5
4
4
4
3
3
3
3
3
3
2
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
325
179
133
133
130
98
90
55
16
7
7
6
6
5
2
2
2
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Human SOX2 recombinant protein is used to produce this monoclonal antibody.
Klon 57CT23-3-4
Isotyp IgG1
Reinigung Ascites
Andere Bezeichnung SOX2 (SOX2 Antibody Abstract)
Hintergrund This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Synonyms: SOX2, Transcription factor SOX-2
NCBI Accession NP_003097
UniProt P48431
Pathways Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Applikations-hinweise IF: 1:200,WB: 1:200-2000,FACS: 1:50-100
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN1882277) Western blot analysis of anti-SOX2 Monoclonal Antibody (ABIN1882277) by human SOX2 re...
Immunofluorescence (IF) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN1882277) Western blot analysis of anti-SOX2 Monoclonal Antibody (ABIN1882277) by human SOX2 re...
Western Blotting (WB) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN1882277) Western blot analysis of anti-SOX2 Monoclonal Antibody (ABIN1882277) by human SOX2 re...
Produkt verwendet in: Reis, Tyler, Schneider, Bardakjian, Semina: "Examination of SOX2 in variable ocular conditions identifies a recurrent deletion in microphthalmia and lack of mutations in other phenotypes." in: Molecular vision, Vol. 16, pp. 768-73, 2010 (PubMed).

Ge, Zhou, Chen, Cui, Liu, Li, Yang, Wu, Sun, Gu, Wei, Jiang: "Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 711-7, 2010 (PubMed).

Sholl, Barletta, Yeap, Chirieac, Hornick: "Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma." in: The American journal of surgical pathology, Vol. 34, Issue 8, pp. 1193-8, 2010 (PubMed).

Zhang, Efendic, Brismar, Gu: "Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus." in: BMC medical genetics, Vol. 11, pp. 116, 2010 (PubMed).

Gonzalez-Rodriguez, Pelcastre, Tovilla-Canales, Garcia-Ortiz, Amato-Almanza, Villanueva-Mendoza, Espinosa-Mattar, Zenteno: "Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases." in: The British journal of ophthalmology, Vol. 94, Issue 8, pp. 1100-4, 2010 (PubMed).

Ross, Spengler, Biedler: "Coordinate morphological and biochemical interconversion of human neuroblastoma cells." in: Journal of the National Cancer Institute, Vol. 71, Issue 4, pp. 741-7, 1983 (PubMed).

Biedler, Roffler-Tarlov, Schachner, Freedman: "Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones." in: Cancer research, Vol. 38, Issue 11 Pt 1, pp. 3751-7, 1978 (PubMed).

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