LOX Antikörper (AA 234-260)
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- Target Alle LOX Antikörper anzeigen
- LOX (Lysyl Oxidase (LOX))
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Bindungsspezifität
- AA 234-260
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LOX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- M, Pig, Rat
- Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
- Klon
- 624CT23-7-3
- Isotyp
- IgG2b
- Top Product
- Discover our top product LOX Primärantikörper
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- Applikationshinweise
- WB: 1:100~500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
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LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).
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- Target
- LOX (Lysyl Oxidase (LOX))
- Andere Bezeichnung
- LOX (LOX Produkte)
- Synonyme
- LOX antikoerper, Xlox antikoerper, MGC146507 antikoerper, lox antikoerper, zgc:77447 antikoerper, AI893619 antikoerper, TSC-160 antikoerper, H-rev142 antikoerper, Rrg1 antikoerper, lysyl oxidase antikoerper, lysyl oxidase a antikoerper, lysyl oxidase L homeolog antikoerper, LOX antikoerper, lox antikoerper, loxa antikoerper, lox.L antikoerper, Lox antikoerper
- Hintergrund
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 46944
- NCBI Accession
- NP_002308
- UniProt
- P28300
- Pathways
- SARS-CoV-2 Protein Interaktom
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