CCRK Antikörper

Produktnummer ABIN1882215

Produktdetails anti-CCRK Antikörper

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCRK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged CCRK protein was used to produced this monoclonal antibody.

Klon: 885CT27-1-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CCRK Antikörper (ABIN1882215)

Wang, Kung: "Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1." in: Oncogene, Vol. 31, Issue 24, pp. 2907-18, (2012) (PubMed).

Liu, Wu, Galaktionov: "p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4507-14, (2004) (PubMed).

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Details zu CCRK

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Andere Bezeichnung: CCRK (CDK20 Produkte)

Synonyme: CCRK antikoerper, CDCH antikoerper, P42 antikoerper, PNQALRE antikoerper, Ccrk antikoerper, 4932702G04Rik antikoerper, AU019450 antikoerper, AW558027 antikoerper, PNQLARE antikoerper, p42 antikoerper, cyclin dependent kinase 20 antikoerper, cyclin-dependent kinase 20 antikoerper, CDK20 antikoerper, Cdk20 antikoerper, cdk20 antikoerper

Hintergrund: Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

Molekulargewicht: 38695

NCBI Accession: NP_001034892, NP_001164110, NP_001164111, NP_036251, NP_848519

UniProt: Q8IZL9