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Sonic Hedgehog Antikörper (AA 151-162)

SHH Reaktivität: Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal RB46723 unconjugated
Produktnummer ABIN1882186
  • Target Alle Sonic Hedgehog (SHH) Antikörper anzeigen
    Sonic Hedgehog (SHH)
    Bindungsspezifität
    • 15
    • 11
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-162
    Reaktivität
    • 62
    • 54
    • 40
    • 17
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Zebrafisch (Danio rerio)
    Wirt
    • 73
    • 10
    • 8
    • 1
    • 1
    Kaninchen
    Klonalität
    • 65
    • 28
    Polyklonal
    Konjugat
    • 53
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sonic Hedgehog Antikörper ist unkonjugiert
    Applikation
    • 73
    • 32
    • 25
    • 14
    • 13
    • 11
    • 11
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This shha antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 151-162 amino acids from the Central region of DANRE shha.
    Klon
    RB46723
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    Discover our top product SHH Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Müller, Chang, Albert, Fischer, Tora, Strähle: "Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord." in: Development (Cambridge, England), Vol. 126, Issue 10, pp. 2103-16, (1999) (PubMed).

    Zardoya, Abouheif, Meyer: "Evolutionary analyses of hedgehog and Hoxd-10 genes in fish species closely related to the zebrafish." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 13036-41, (1996) (PubMed).

    Ekker, Ungar, Greenstein, von Kessler, Porter, Moon, Beachy: "Patterning activities of vertebrate hedgehog proteins in the developing eye and brain." in: Current biology : CB, Vol. 5, Issue 8, pp. 944-55, (1995) (PubMed).

    Roelink, Augsburger, Heemskerk, Korzh, Norlin, Ruiz i Altaba, Tanabe, Placzek, Edlund, Jessell: "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord." in: Cell, Vol. 76, Issue 4, pp. 761-75, (1994) (PubMed).

  • Target
    Sonic Hedgehog (SHH)
    Andere Bezeichnung
    shha (SHH Produkte)
    Synonyme
    HHG1 antikoerper, HLP3 antikoerper, HPE3 antikoerper, MCOPCB5 antikoerper, SMMCI antikoerper, TPT antikoerper, TPTPS antikoerper, 9530036O11Rik antikoerper, Dsh antikoerper, Hhg1 antikoerper, Hx antikoerper, Hxl3 antikoerper, M100081 antikoerper, fc83d08 antikoerper, shh antikoerper, syu antikoerper, vhh-1 antikoerper, vhh1 antikoerper, wu:fc83d08 antikoerper, Xhh antikoerper, hedgehog antikoerper, xshh antikoerper, SHH antikoerper, twh antikoerper, twhh antikoerper, sonic hedgehog antikoerper, sonic hedgehog a antikoerper, sonic hedgehog L homeolog antikoerper, sonic hedgehog protein A antikoerper, sonic hedgehog b antikoerper, SHH antikoerper, Shh antikoerper, shha antikoerper, shh.L antikoerper, shh antikoerper, shhb antikoerper
    Hintergrund
    Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
    Molekulargewicht
    46403
    UniProt
    Q92008
    Pathways
    Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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