UBE2L3 Antikörper (C-Term)

Produktnummer ABIN1882145

Produktdetails anti-UBE2L3 Antikörper

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Bindungsspezifität: AA 123-153, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2L3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L3.

Klon: RB4154

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-UBE2L3 Antikörper (ABIN1882145)

Moynihan, Cole, Dunham, ONeil, Markham, Robinson: "Fine-mapping, genomic organization, and transcript analysis of the human ubiquitin-conjugating enzyme gene UBE2L3." in: Genomics, Vol. 51, Issue 1, pp. 124-7, (1998) (PubMed).

Moynihan, Ardley, Leek, Thompson, Brindle, Markham, Robinson: "Characterization of a human ubiquitin-conjugating enzyme gene UBE2L3." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 7, Issue 7, pp. 520-5, (1996) (PubMed).

Nuber, Schwarz, Kaiser, Schneider, Scheffner: "Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5." in: The Journal of biological chemistry, Vol. 271, Issue 5, pp. 2795-800, (1996) (PubMed).

Robinson, Leek, Thompson, Carr, Bailey, Moynihan, Coletta, Lench, Markham: "A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 6, Issue 10, pp. 725-31, (1996) (PubMed).

Details zu UBE2L3

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Andere Bezeichnung: UBE2L3 (UBE2L3 Produkte)

Synonyme: E2-F1 antikoerper, L-UBC antikoerper, UBCH7 antikoerper, UbcM4 antikoerper, C79827 antikoerper, Ubce7 antikoerper, ube2l3 antikoerper, wu:fc22h11 antikoerper, zgc:86727 antikoerper, UBE2L3 antikoerper, ube2l3l antikoerper, wu:fb38h03 antikoerper, ubiquitin conjugating enzyme E2 L3 antikoerper, ubiquitin-conjugating enzyme E2L 3 antikoerper, ubiquitin-conjugating enzyme E2L 3a antikoerper, ubiquitin conjugating enzyme E2 L3 S homeolog antikoerper, ubiquitin-conjugating enzyme E2L 3b antikoerper, UBE2L3 antikoerper, Ube2l3 antikoerper, ube2l3a antikoerper, ube2l3.S antikoerper, ube2l3b antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.

Molekulargewicht: 17862

NCBI Accession: NP_001243284, NP_001243285, NP_003338

UniProt: P68036