CAMKK2 Antikörper (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta) (AA 483-512)

Details for Product anti-CAMKK2 Antibody No. ABIN1882069
Antigen
  • CAMKK
  • CAMKKB
  • 6330570N16Rik
  • AW061083
  • mKIAA0787
  • camk2b
  • fj90d04
  • wu:fj90d04
  • si:dkey-174n20.2
  • CAMKK2
  • calcium/calmodulin dependent protein kinase kinase 2
  • calcium/calmodulin-dependent protein kinase kinase 2, beta
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
  • calcium/calmodulin dependent protein kinase II beta
  • calcium/calmodulin-dependent protein kinase kinase 2
  • CAMKK2
  • Camkk2
  • camk2b1
  • CAMK2B
  • camkk2
Epitop
AA 483-512, C-Term
22
11
11
7
7
7
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human
115
68
36
3
2
2
2
1
1
1
1
1
1
Wirt
Kaninchen
119
14
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser CAMKK2 Antikörper ist unkonjugiert
8
6
6
4
4
4
3
3
3
3
3
3
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
102
56
36
16
13
7
6
5
3
1
1
1
Optionen
Immunogen This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human CAMKK2.
Klon RB12560
Homologie Mouse (Murine),Rat (Rattus)
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Plasmids, Primers & others Plasmide, Primers & weitere CAMKK2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CAMKK2 (CAMKK2 Antibody Abstract)
Hintergrund CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.

Synonyms: CAMKK2, CAMKKB, KIAA0787, Calcium/calmodulin-dependent protein kinase kinase 2, Calcium/calmodulin-dependent protein kinase kinase beta
NCBI Accession NP_001257415, NP_006540, NP_757363, NP_757364, NP_757365, NP_757380, NP_705719, NP_705720, NP_001257414
UniProt Q96RR4
Pathways AMPK Signaling
Applikations-hinweise WB: 1:1000,IHC (p): 1:50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512), (C-Term) antibody (ABIN1882069) Western blot analysis of CAMKK2 (arrow) using rabbit polyclonal CAMKK2 Antibody (C-te...
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512), (C-Term) antibody (ABIN1882069) Western blot analysis of CAMKK2 (arrow) using rabbit polyclonal CAMKK2 Antibody (C-te...
Produkt verwendet in: Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, 2015 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

Goravanahally, Salem, Yao, Inskeep, Flores: "Differential gene expression in the bovine corpus luteum during transition from early phase to midphase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2 alpha." in: Biology of reproduction, Vol. 80, Issue 5, pp. 980-8, 2009 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

Hsu, Chen, Lee, Chi, Cheng, Chen: "Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity." in: The Journal of biological chemistry, Vol. 276, Issue 33, pp. 31113-23, 2001 (PubMed).

Hsu, Tsou, Chi, Lee, Chen: "Cloning, expression and chromosomal localization of human Ca2+/calmodulin-dependent protein kinase kinase." in: Journal of biomedical science, Vol. 5, Issue 2, pp. 141-9, 1998 (PubMed).

Anderson, Means, Huang, Kemp, Goldstein, Selbert, Edelman, Fremeau, Means: "Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31880-9, 1998 (PubMed).

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