ZRSR2 Antikörper (C-Term)

Produktnummer ABIN1882041

Produktdetails anti-ZRSR2 Antikörper

Target: ZRSR2 (Zinc Finger (CCCH Type), RNA-Binding Motif and serine/arginine Rich 2 (ZRSR2))

Bindungsspezifität: AA 453-482, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZRSR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZRSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human ZRSR2.

Klon: RB44050

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ZRSR2 Antikörper (ABIN1882041)

Will, Schneider, Hossbach, Urlaub, Rauhut, Elbashir, Tuschl, Lührmann: "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome." in: RNA (New York, N.Y.), Vol. 10, Issue 6, pp. 929-41, (2004) (PubMed).

Scanlan, Gordan, Williamson, Stockert, Bander, Jongeneel, Gure, Jäger, Jäger, Knuth, Chen, Old: "Antigens recognized by autologous antibody in patients with renal-cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 83, Issue 4, pp. 456-64, (1999) (PubMed).

Tronchère, Wang, Fu: "A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA." in: Nature, Vol. 388, Issue 6640, pp. 397-400, (1997) (PubMed).

Kitagawa, Wang, Hatada, Yamaoka, Nojima, Inazawa, Abe, Mitsuya, Oshimura, Murata: "Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1." in: Genomics, Vol. 30, Issue 2, pp. 257-63, (1996) (PubMed).

Details zu ZRSR2

Target: ZRSR2 (Zinc Finger (CCCH Type), RNA-Binding Motif and serine/arginine Rich 2 (ZRSR2))

Andere Bezeichnung: ZRSR2 (ZRSR2 Produkte)

Synonyme: ZRSR2 antikoerper, 35kDa antikoerper, 5031411E02Rik antikoerper, A230052C13Rik antikoerper, C77286 antikoerper, U2af1-rs2 antikoerper, URP antikoerper, RGD1559763 antikoerper, U2AF1-RS2 antikoerper, U2AF1L2 antikoerper, U2AF1RS2 antikoerper, fb73a09 antikoerper, wu:fb73a09 antikoerper, zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 antikoerper, zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 antikoerper, zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 antikoerper, ZRSR2 antikoerper, zrsr2 antikoerper, ZRSR2Y antikoerper, Zrsr2 antikoerper

Hintergrund: Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.

Molekulargewicht: 58045

NCBI Accession: NP_005080

UniProt: Q15696

Pathways: Ribonucleoprotein Complex Subunit Organization