UBR7 Antikörper (N-Term)

Produktnummer ABIN1881973

Produktdetails anti-UBR7 Antikörper

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Bindungsspezifität: AA 100-128, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of human UBR7.

Klon: RB40614

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-UBR7 Antikörper (ABIN1881973)

Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, (2008) (PubMed).

Kiechl, Werner, Knoflach, Furtner, Willeit, Schett: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Expert review of cardiovascular therapy, Vol. 4, Issue 6, pp. 801-11, (2006) (PubMed).

Details zu UBR7

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Andere Bezeichnung: UBR7 (UBR7 Produkte)

Synonyme: C14orf130 antikoerper, 5730410I19Rik antikoerper, AA589405 antikoerper, AW557761 antikoerper, RGD1359144 antikoerper, ubiquitin protein ligase E3 component n-recognin 7 (putative) antikoerper, UBR7 antikoerper, Ubr7 antikoerper

Hintergrund: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).

Molekulargewicht: 47999

NCBI Accession: NP_786924

UniProt: Q8N806