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TXNIP Antikörper (AA 116-145)

TXNIP Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB30652 unconjugated
Produktnummer ABIN1881961
  • Target Alle TXNIP Antikörper anzeigen
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Bindungsspezifität
    • 16
    • 14
    • 9
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-145
    Reaktivität
    • 63
    • 46
    • 32
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 71
    • 5
    Kaninchen
    Klonalität
    • 62
    • 14
    Polyklonal
    Konjugat
    • 31
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TXNIP Antikörper ist unkonjugiert
    Applikation
    • 58
    • 32
    • 16
    • 14
    • 14
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
    Klon
    RB30652
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TXNIP Primärantikörper
  • Applikationshinweise
    WB: 1:2000. IHC-P: 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Martin: "[Growing old]." in: Revue médicale suisse, Vol. 6, Issue 256, pp. 1424, (2010) (PubMed).

    Kwon, Lim, Han, Lee, Yoon, Nam, Choi, Kim, Won, Kim: "The role of vitamin D3 upregulated protein 1 in thioacetamide-induced mouse hepatotoxicity." in: Toxicology and applied pharmacology, Vol. 248, Issue 3, pp. 277-84, (2010) (PubMed).

    Kwon, Won, Suh, Jeon, Shao, Yoon, Chung, Kim, Kim, Nam, Yoon, Kim, Kim, Kim, Kim, Kim, Choi: "Vitamin D3 upregulated protein 1 suppresses TNF-?-induced NF-?B activation in hepatocarcinogenesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3980-9, (2010) (PubMed).

    Ren, Shi, Wang, Li, Wu, Li, Zhang, Duan: "p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells." in: FEBS letters, Vol. 584, Issue 15, pp. 3480-5, (2010) (PubMed).

    Shao, Kim, Shin, Kim, Suh, Piao, Jeong, Lee, Yoon, Lim, Kim, Ahn, Choi: "TXNIP regulates germinal center generation by suppressing BCL-6 expression." in: Immunology letters, Vol. 129, Issue 2, pp. 78-84, (2010) (PubMed).

  • Target
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Andere Bezeichnung
    Txnip (TXNIP Produkte)
    Synonyme
    EST01027 antikoerper, HHCPA78 antikoerper, THIF antikoerper, VDUP1 antikoerper, Gm348 antikoerper, Trf3 antikoerper, TBP2 antikoerper, TRF3 antikoerper, 1200008J08Rik antikoerper, AA682105 antikoerper, Hyplip1 antikoerper, Tbp-2 antikoerper, Vdup1 antikoerper, sb:cb368 antikoerper, txnip antikoerper, thioredoxin interacting protein antikoerper, TATA box binding protein like 2 antikoerper, TATA-box binding protein like 2 antikoerper, thioredoxin interacting protein L homeolog antikoerper, thioredoxin interacting protein a antikoerper, TXNIP antikoerper, Tbpl2 antikoerper, TBPL2 antikoerper, Txnip antikoerper, txnip.L antikoerper, txnip antikoerper, txnipa antikoerper
    Hintergrund
    May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
    Molekulargewicht
    44363
    NCBI Accession
    NP_001009935, NP_076208
    UniProt
    Q8BG60
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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