RNASE1 Antikörper (N-Term)

Produktnummer ABIN1881752

Produktdetails anti-RNASE1 Antikörper

Target: RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))

Bindungsspezifität: AA 14-42, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNASE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNASE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RNASE1.

Klon: RB42410

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-RNASE1 Antikörper (ABIN1881752)

DAlessio: "It takes two to flirt with a dimeric RNase." in: Biopolymers, Vol. 91, Issue 12, pp. 989-94, (2009) (PubMed).

Kövér, Bruix, Santoro, Batta, Laurents, Rico: "The solution structure and dynamics of human pancreatic ribonuclease determined by NMR spectroscopy provide insight into its remarkable biological activities and inhibition." in: Journal of molecular biology, Vol. 379, Issue 5, pp. 953-65, (2008) (PubMed).

Cybulski, Wokołorczyk, Jakubowska, Gliniewicz, Sikorski, Huzarski, Debniak, Narod, Lubiński: "DNA variation in MSR1, RNASEL and E-cadherin genes and prostate cancer in Poland." in: Urologia internationalis, Vol. 79, Issue 1, pp. 44-9, (2007) (PubMed).

Details zu RNASE1

Target: RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))

Andere Bezeichnung: RNASE1 (RNASE1 Produkte)

Synonyme: RNASE1 antikoerper, RNS1 antikoerper, ATRNS1 antikoerper, RIBONUCLEASE 1 antikoerper, T17M13.16 antikoerper, T17M13_16 antikoerper, ribonuclease 1 antikoerper, RIB1 antikoerper, AI574248 antikoerper, Rib-1 antikoerper, Rib1 antikoerper, SRN antikoerper, ribonuclease A family member 1, pancreatic antikoerper, ribonuclease pancreatic-like antikoerper, ribonuclease A family member k6 antikoerper, Ribonuclease 1 antikoerper, ribonuclease 1 antikoerper, ribonuclease, RNase A family, 1 (pancreatic) antikoerper, ribonuclease pancreatic antikoerper, RNASE1 antikoerper, LOC475395 antikoerper, RNASE6 antikoerper, Rnase1 antikoerper, RNS1 antikoerper, LOC101113761 antikoerper

Hintergrund: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq].

Molekulargewicht: 17644

NCBI Accession: NP_002924, NP_937875, NP_937877, NP_937878

UniProt: P07998