PPP2R2A Antikörper (N-Term)

Produktnummer ABIN1881683

Produktdetails anti-PPP2R2A Antikörper

Target: PPP2R2A (Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A))

Bindungsspezifität: AA 43-71, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pr, M, Pig, Rb, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP2R2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human PPP2R2A.

Klon: RB43624

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PPP2R2A Antikörper (ABIN1881683)

Li, Cai, Shouse, Piluso, Liu: "A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55." in: The EMBO journal, Vol. 26, Issue 2, pp. 402-11, (2007) (PubMed).

Nusbaum, Mikkelsen, Zody, Asakawa, Taudien, Garber, Kodira, Schueler, Shimizu, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Allen, Anderson, Asakawa, Blechschmidt, Bloom, Borowsky, Butler, Cook et al.: "DNA sequence and analysis of human chromosome 8. ..." in: Nature, Vol. 439, Issue 7074, pp. 331-5, (2006) (PubMed).

Mayer, Hendrix, Cron, Matthies, Stone, Goris, Merlevede, Hofsteenge, Hemmings: "Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform." in: Biochemistry, Vol. 30, Issue 15, pp. 3589-97, (1991) (PubMed).

Details zu PPP2R2A

Target: PPP2R2A (Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A))

Andere Bezeichnung: PPP2R2A (PPP2R2A Produkte)

Synonyme: B55A antikoerper, B55ALPHA antikoerper, PR52A antikoerper, PR55A antikoerper, 2410004D02Rik antikoerper, mKIAA1541 antikoerper, PPP2R2A antikoerper, protein phosphatase 2 regulatory subunit Balpha antikoerper, protein phosphatase 2, regulatory subunit B, alpha antikoerper, PPP2R2A antikoerper, Ppp2r2a antikoerper

Hintergrund: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Molekulargewicht: 51692

NCBI Accession: NP_001171062, NP_002708

UniProt: P63151

Pathways: Mitotic G1-G1/S Phases, Hepatitis C