PCSK5 Antikörper (N-Term)

Produktnummer ABIN1881639

Produktdetails anti-PCSK5 Antikörper

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Bindungsspezifität: AA 95-124, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCSK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the N-terminal region of human PCSK5.

Klon: RB41935

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PCSK5 Antikörper (ABIN1881639)

Heng, Paule, Hardman, Li, Singh, Rainczuk, Stephens, Nie: "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment." in: Endocrinology, Vol. 151, Issue 8, pp. 3909-17, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Iatan, Dastani, Do, Weissglas-Volkov, Ruel, Lee, Huertas-Vazquez, Taskinen, Prat, Seidah, Pajukanta, Engert, Genest: "Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 467-75, (2009) (PubMed).

Details zu PCSK5

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Andere Bezeichnung: PCSK5 (PCSK5 Produkte)

Synonyme: PC5 antikoerper, PC6 antikoerper, PC6A antikoerper, SPC6 antikoerper, subtilase antikoerper, PC5/6A antikoerper, PC5A antikoerper, b2b1549Clo antikoerper, b2b585Clo antikoerper, Pc5 antikoerper, fur2 antikoerper, spc6 antikoerper, spc6A antikoerper, MGC98915 antikoerper, PCSK5 antikoerper, pc6 antikoerper, spc6a antikoerper, pcsk5 antikoerper, zgc:165659 antikoerper, proprotein convertase subtilisin/kexin type 5 antikoerper, proprotein convertase subtilisin/kexin type 5 S homeolog antikoerper, proprotein convertase subtilisin/kexin type 5b antikoerper, PCSK5 antikoerper, Pcsk5 antikoerper, pcsk5.S antikoerper, LOC528098 antikoerper, pcsk5 antikoerper, pcsk5b antikoerper

Hintergrund: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 206942

NCBI Accession: NP_001177411, NP_006191

UniProt: Q92824

Pathways: Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones