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GPR68 Antikörper (AA 200-225)

GPR68 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1881516
  • Target Alle GPR68 Antikörper anzeigen
    GPR68 (G Protein-Coupled Receptor 68 (GPR68))
    Bindungsspezifität
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-225
    Reaktivität
    • 48
    • 27
    • 16
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    Maus
    Wirt
    • 48
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 40
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GPR68 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 16
    • 16
    • 11
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, H
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Gpr68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-225 amino acids from the Central region of mouse Gpr68.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GPR68 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Frick, Krieger, Nehrke, Bushinsky: "Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 2, pp. 305-13, (2009) (PubMed).

    Singh, Berk, Oates, Zhao, Tan, Jiang, Zhou, Kirmani, Steinmetz, Lindner, Xu: "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer." in: Journal of the National Cancer Institute, Vol. 99, Issue 17, pp. 1313-27, (2007) (PubMed).

  • Target
    GPR68 (G Protein-Coupled Receptor 68 (GPR68))
    Andere Bezeichnung
    Gpr68 (GPR68 Produkte)
    Synonyme
    GPR68 antikoerper, GPR12A antikoerper, OGR1 antikoerper, BB131428 antikoerper, Ogr1 antikoerper, G protein-coupled receptor 68 antikoerper, GPR68 antikoerper, LOC100348269 antikoerper, Gpr68 antikoerper
    Hintergrund
    Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
    Molekulargewicht
    41209
    NCBI Accession
    NP_001171144, NP_001171145, NP_780702
    UniProt
    Q8BFQ3
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