LRCH1 Antikörper (AA 304-333)

Produktnummer ABIN1881505

Produktdetails anti-LRCH1 Antikörper

Target: LRCH1 (Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 1 (LRCH1))

Bindungsspezifität: AA 304-333

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRCH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LRCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human LRCH1.

Klon: RB42699

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-LRCH1 Antikörper (ABIN1881505)

Zintzaras, Kitsios, Ziogas, Rodopoulou, Karachalios: "Field synopsis and synthesis of genetic association studies in osteoarthritis: the CUMAGAS-OSTEO information system." in: American journal of epidemiology, Vol. 171, Issue 8, pp. 851-8, (2010) (PubMed).

Jiang, Shi, Nakajima, Dai, Wei, Malizos, Qin, Miyamoto, Kamatani, Liu, Tsezou, Nakamura, Ikegawa: "Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility." in: Journal of human genetics, Vol. 53, Issue 1, pp. 42-7, (2007) (PubMed).

Ikegawa: "New gene associations in osteoarthritis: what do they provide, and where are we going?" in: Current opinion in rheumatology, Vol. 19, Issue 5, pp. 429-34, (2007) (PubMed).

Snelling, Sinsheimer, Carr, Loughlin: "Genetic association analysis of LRCH1 as an osteoarthritis susceptibility locus." in: Rheumatology (Oxford, England), Vol. 46, Issue 2, pp. 250-2, (2007) (PubMed).

Spector, Reneland, Mah, Valdes, Hart, Kammerer, Langdown, Hoyal, Atienza, Doherty, Rahman, Nelson, Braun: "Association between a variation in LRCH1 and knee osteoarthritis: a genome-wide single-nucleotide polymorphism association study using DNA pooling." in: Arthritis and rheumatism, Vol. 54, Issue 2, pp. 524-32, (2006) (PubMed).

Details zu LRCH1

Target: LRCH1 (Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 1 (LRCH1))

Andere Bezeichnung: LRCH1 (LRCH1 Produkte)

Synonyme: CHDC1 antikoerper, NP81 antikoerper, 4832412D13Rik antikoerper, AI552548 antikoerper, AW215503 antikoerper, Chdc1 antikoerper, mKIAA1016 antikoerper, leucine rich repeats and calponin homology domain containing 1 antikoerper, leucine-rich repeats and calponin homology (CH) domain containing 1 antikoerper, Lrch1 antikoerper, LRCH1 antikoerper

Hintergrund: This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism in this gene may be associated with susceptibililty to knee osteoarthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 80875

NCBI Accession: NP_001157683, NP_001157685, NP_055931

UniProt: Q9Y2L9