LGALS3BP Antikörper (AA 383-412)

Produktnummer ABIN1881492

Produktdetails anti-LGALS3BP Antikörper

Target: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Bindungsspezifität: AA 383-412

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGALS3BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.

Klon: RB40516

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000. IHC-P-Leica: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-LGALS3BP Antikörper (ABIN1881492)

Srirajaskanthan, Caplin, Waugh, Watkins, Meyer, Hsuan, Beaumont: "Identification of Mac-2-binding protein as a putative marker of neuroendocrine tumors from the analysis of cell line secretomes." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 4, pp. 656-66, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Zambelli, Zuntini, Nardi, Manara, Serra, Landuzzi, Lollini, Ferrari, Alberghini, Llombart-Bosch, Piccolo, Iacobelli, Picci, Scotlandi: "Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP)." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 1, pp. 41-52, (2009) (PubMed).

Lee, Zhang, Shin, Lee, Kim: "Mac-2 binding protein and galectin-3 expression in mucinous tumours of the ovary: an annealing control primer system and immunohistochemical study." in: Pathology, Vol. 41, Issue 3, pp. 229-33, (2009) (PubMed).

Kim, Lee, Sung, Choi, Choi, Kim, Kim, Yu, Hwang, Kim: "Increased serum 90K and Galectin-3 expression are associated with advanced stage and a worse prognosis in diffuse large B-cell lymphomas." in: Acta haematologica, Vol. 120, Issue 4, pp. 211-6, (2009) (PubMed).

Details zu LGALS3BP

Target: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Andere Bezeichnung: LGALS3BP (LGALS3BP Produkte)

Synonyme: 90K antikoerper, BTBD17B antikoerper, MAC-2-BP antikoerper, TANGO10B antikoerper, Ppicap antikoerper, CyCAP antikoerper, MAC-2BP antikoerper, Tango10b antikoerper, lgals3bp antikoerper, zgc:136780 antikoerper, MAC2BP antikoerper, Mac-2 BP antikoerper, zgc:77059 antikoerper, galectin 3 binding protein antikoerper, lectin, galactoside-binding, soluble, 3 binding protein antikoerper, calcium activated nucleotidase 1 antikoerper, lectin, galactoside-binding, soluble, 3 binding protein a antikoerper, lectin, galactoside-binding, soluble, 3 binding protein b antikoerper, LGALS3BP antikoerper, Lgals3bp antikoerper, CANT1 antikoerper, lgals3bpa antikoerper, lgals3bpb antikoerper

Hintergrund: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

NCBI Accession: NP_005558

UniProt: Q08380