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ILKAP Antikörper (AA 93-122)

ILKAP Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40435 unconjugated
Produktnummer ABIN1881459
  • Target Alle ILKAP Antikörper anzeigen
    ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))
    Bindungsspezifität
    • 14
    • 12
    • 10
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-122
    Reaktivität
    • 55
    • 24
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 49
    • 5
    • 2
    Kaninchen
    Klonalität
    • 54
    • 2
    Polyklonal
    Konjugat
    • 23
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ILKAP Antikörper ist unkonjugiert
    Applikation
    • 45
    • 39
    • 17
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Homologie
    B, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.
    Klon
    RB40435
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ILKAP Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Nakrieko, Vespa, Mason, Irvine, DSouza, Dagnino: "Modulation of integrin-linked kinase nucleo-cytoplasmic shuttling by ILKAP and CRM1." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 14, pp. 2157-66, (2008) (PubMed).

    Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

    Kumar, Naruszewicz, Wang, Leung-Hagesteijn, Hannigan: "ILKAP regulates ILK signaling and inhibits anchorage-independent growth." in: Oncogene, Vol. 23, Issue 19, pp. 3454-61, (2004) (PubMed).

  • Target
    ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))
    Andere Bezeichnung
    ILKAP (ILKAP Produkte)
    Synonyme
    MGC84595 antikoerper, MGC107938 antikoerper, ILKAP antikoerper, ILKAP2 antikoerper, ILKAP3 antikoerper, PP2C-DELTA antikoerper, 0710007A14Rik antikoerper, 1600009O09Rik antikoerper, ILK associated serine/threonine phosphatase antikoerper, ILK associated serine/threonine phosphatase L homeolog antikoerper, integrin-linked kinase-associated serine/threonine phosphatase antikoerper, integrin-linked kinase-associated serine/threonine phosphatase 2C antikoerper, ILKAP antikoerper, ilkap.L antikoerper, ilkap antikoerper, Ilkap antikoerper
    Hintergrund
    The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
    Molekulargewicht
    42907
    NCBI Accession
    NP_110395
    UniProt
    Q9H0C8
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