HEY2 Antikörper (C-Term)

Produktnummer ABIN1881411

Produktdetails anti-HEY2 Antikörper

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Bindungsspezifität: AA 295-322, C-Term

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DANRE hey2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the C-terminal region of DANRE hey2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-HEY2 Antikörper (ABIN1881411)

Winkler, Elmasri, Klamt, Volff, Gessler: "Characterization of hey bHLH genes in teleost fish." in: Development genes and evolution, Vol. 213, Issue 11, pp. 541-53, (2003) (PubMed).

Zhong, Childs, Leu, Fishman: "Gridlock signalling pathway fashions the first embryonic artery." in: Nature, Vol. 414, Issue 6860, pp. 216-20, (2001) (PubMed).

Zhong, Rosenberg, Mohideen, Weinstein, Fishman: "gridlock, an HLH gene required for assembly of the aorta in zebrafish." in: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1820-4, (2000) (PubMed).

Details zu HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Andere Bezeichnung: hey2 (HEY2 Produkte)

Synonyme: CHF1 antikoerper, GRIDLOCK antikoerper, GRL antikoerper, HERP1 antikoerper, HESR2 antikoerper, HRT2 antikoerper, bHLHb32 antikoerper, Herp1 antikoerper, Hrt2 antikoerper, hesr2 antikoerper, grl antikoerper, zgc:136746 antikoerper, hes related family bHLH transcription factor with YRPW motif 2 antikoerper, hairy/enhancer-of-split related with YRPW motif 2 antikoerper, hes-related family bHLH transcription factor with YRPW motif 2 antikoerper, HEY2 antikoerper, Hey2 antikoerper, hey2 antikoerper

Hintergrund: Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.

Molekulargewicht: 34329

NCBI Accession: NP_571697

UniProt: Q9I9L0

Pathways: Regulation of Muscle Cell Differentiation