GRIN2C Antikörper (AA 567-595)

Produktnummer ABIN1881390

Produktdetails anti-GRIN2C Antikörper

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Bindungsspezifität: AA 567-595

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.

Klon: RB40514

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GRIN2C Antikörper (ABIN1881390)

Need, Keefe, Ge, Grossman, Dickson, McEvoy, Goldstein: "Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis." in: European journal of human genetics : EJHG, Vol. 17, Issue 7, pp. 946-57, (2009) (PubMed).

Krapivinsky, Krapivinsky, Manasian, Ivanov, Tyzio, Pellegrino, Ben-Ari, Clapham, Medina: "The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1." in: Neuron, Vol. 40, Issue 4, pp. 775-84, (2003) (PubMed).

Self, Mulholland, Nath, Harris, Prendergast: "The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site." in: Brain research, Vol. 995, Issue 1, pp. 39-45, (2003) (PubMed).

Details zu GRIN2C

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Andere Bezeichnung: GRIN2C (GRIN2C Produkte)

Synonyme: GRIN2C antikoerper, NMDAR2C antikoerper, il12rb2l antikoerper, il-12rb2.b antikoerper, nr2c antikoerper, GluN2C antikoerper, NR2C antikoerper, glutamate ionotropic receptor NMDA type subunit 2C antikoerper, interleukin 12 receptor, beta 2a, like antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2C antikoerper, glutamate receptor, ionotropic, NMDA2C (epsilon 3) antikoerper, GRIN2C antikoerper, il12rb2l antikoerper, grin2c.S antikoerper, grin2c antikoerper, Grin2c antikoerper

Hintergrund: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq].

Molekulargewicht: 134209

NCBI Accession: NP_000826

UniProt: Q14957

Pathways: Synaptic Membrane