GNA11 Antikörper (N-Term)

Produktnummer ABIN1881378

Produktdetails anti-GNA11 Antikörper

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNA11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Pig, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GNA11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GNA11.

Klon: RB30618

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GNA11 Antikörper (ABIN1881378)

Zhao, Zou, Li, Li, Wu, Li, Wang, Zheng: "Expression of G-protein subunit ?-14 is increased in human placentas from preeclamptic pregnancies." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 62, Issue 5, pp. 347-54, (2014) (PubMed).

Gavard, Gutkind: "Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q." in: The Journal of biological chemistry, Vol. 283, Issue 44, pp. 29888-96, (2008) (PubMed).

Durchánková, Novotný, Svoboda: "The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis." in: Physiological research / Academia Scientiarum Bohemoslovaca, Vol. 57, Issue 2, pp. 195-203, (2008) (PubMed).

Shankaranarayanan, Thal, Tesmer, Roman, Neubig, Kozasa, Tesmer: "Assembly of high order G alpha q-effector complexes with RGS proteins." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34923-34, (2008) (PubMed).

Luttrell: "Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors." in: Molecular biotechnology, Vol. 39, Issue 3, pp. 239-64, (2008) (PubMed).

Hildebrand, David, Hamid, Mulatz, Garcia, Zamponi, Snutch: "Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors." in: The Journal of biological chemistry, Vol. 282, Issue 29, pp. 21043-55, (2007) (PubMed).

Details zu GNA11

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Andere Bezeichnung: GNA11 (GNA11 Produkte)

Synonyme: Dsk7 antikoerper, E430025L19 antikoerper, GNA-11 antikoerper, HHC2 antikoerper, HYPOC2 antikoerper, G-alpha-11 antikoerper, gna11 antikoerper, si:dkey-42p8.2 antikoerper, wu:fb12d06 antikoerper, zgc:101761 antikoerper, guanine nucleotide binding protein, alpha 11 antikoerper, G protein subunit alpha 11 antikoerper, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) antikoerper, guanine nucleotide regulatory protein G11 alpha subunit antikoerper, guanine nucleotide binding protein (G protein), alpha 11a (Gq class) antikoerper, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) S homeolog antikoerper, guanine nucleotide binding protein (G protein), alpha 11b (Gq class) antikoerper, Gna11 antikoerper, GNA11 antikoerper, gna11 antikoerper, gna11a antikoerper, gna11.S antikoerper, gna11b antikoerper

Hintergrund: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.

Molekulargewicht: 42123

NCBI Accession: NP_002058

UniProt: P29992

Pathways: G-protein mediated Events