DARC Antikörper (N-Term)

Produktnummer ABIN1881251

Produktdetails anti-DARC Antikörper

Target: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DARC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DARC.

Klon: RB42735

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-DARC Antikörper (ABIN1881251)

Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Le Goff, Brès, Rigal, Blum, Marquette: "Robust, high-throughput solution for blood group genotyping." in: Analytical chemistry, Vol. 82, Issue 14, pp. 6185-92, (2010) (PubMed).

Di Cristofaro, Silvy, Chiaroni, Bailly: "Single PCR multiplex SNaPshot reaction for detection of eleven blood group nucleotide polymorphisms: optimization, validation, and one year of routine clinical use." in: The Journal of molecular diagnostics : JMD, Vol. 12, Issue 4, pp. 453-60, (2010) (PubMed).

Details zu DARC

Target: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Andere Bezeichnung: DARC (DARC Produkte)

Synonyme: DARC antikoerper, FY antikoerper, ACKR1 antikoerper, CCBP1 antikoerper, CD234 antikoerper, Dfy antikoerper, GPD antikoerper, GpFy antikoerper, WBCQ1 antikoerper, AA162249 antikoerper, Ackr1 antikoerper, ESTM35 antikoerper, Duffy blood group, chemokine receptor antikoerper, atypical chemokine receptor 1 (Duffy blood group) antikoerper, atypical chemokine receptor 1 antikoerper, DARC antikoerper, ACKR1 antikoerper, Ackr1 antikoerper

Hintergrund: The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 35553

NCBI Accession: NP_001116423, NP_002027

UniProt: Q16570