CHM Antikörper (AA 292-320)
(1 reference)-
- Target Alle CHM Antikörper anzeigen
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
-
Bindungsspezifität
- AA 292-320
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CHM Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CHM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-320 amino acids from the Central region of human CHM.
- Klon
- RB42411
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CHM Primärantikörper
-
anti-Choroideremia (Rab Escort Protein 1) (CHM) (C-Term) antibody
CHM Reaktivität: Human, Ratte, Maus, Pferd, Schaf, Kaninchen, Schwein, Affe, Hamster, Meerschweinchen, Ziege, Esel, Hund, Rind (Kuh), Huhn, Cat, Avian WB Wirt: Ziege Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-653) antibodyCHM Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-80) antibodyCHM Reaktivität: Human, Ratte, Maus, Pferd, Schaf, Kaninchen, Schwein, Affe, Hamster, Meerschweinchen, Ziege, Esel, Hund, Rind (Kuh), Huhn, Cat, Avian WB Wirt: Ziege Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 120-210) antibodyCHM Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 35-84) antibodyCHM Reaktivität: Human, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (N-Term) antibodyCHM Reaktivität: Human, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
-
-
: "Progression of retinal pigment epithelial alterations during long-term follow-up in female carriers of choroideremia and report of a novel CHM mutation." in: Archives of ophthalmology, Vol. 127, Issue 7, pp. 907-12, (2009) (PubMed).
-
: "Progression of retinal pigment epithelial alterations during long-term follow-up in female carriers of choroideremia and report of a novel CHM mutation." in: Archives of ophthalmology, Vol. 127, Issue 7, pp. 907-12, (2009) (PubMed).
-
- Target
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- Andere Bezeichnung
- CHM (CHM Produkte)
- Hintergrund
- This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molekulargewicht
- 73476
- NCBI Accession
- NP_000381, NP_001138886
- UniProt
- P24386
- Pathways
- Sensory Perception of Sound
-
