CDK14 Antikörper (N-Term)

Produktnummer ABIN1881191

Produktdetails anti-CDK14 Antikörper

Target: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Bindungsspezifität: AA 45-72, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14.

Klon: RB40562

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CDK14 Antikörper (ABIN1881191)

Quina, Wang, Ng, Turner: "Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 45, pp. 14309-22, (2009) (PubMed).

Jiang, Gao, Yang, Zhu, Chen: "Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1." in: FEBS letters, Vol. 583, Issue 13, pp. 2171-8, (2009) (PubMed).

Details zu CDK14

Target: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Andere Bezeichnung: Cdk14 (CDK14 Produkte)

Synonyme: PFTK1 antikoerper, PFTAIRE1 antikoerper, Pftk1 antikoerper, mKIAA0834 antikoerper, pftaire1 antikoerper, pftk1 antikoerper, cyclin dependent kinase 14 antikoerper, cyclin-dependent kinase 14 antikoerper, cyclin-dependent kinase 14 L homeolog antikoerper, CDK14 antikoerper, Cdk14 antikoerper, cdk14.L antikoerper

Hintergrund: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).

Molekulargewicht: 52996

NCBI Accession: NP_035204

UniProt: O35495