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CASR Antikörper (AA 260-287)

CASR Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB41198 unconjugated
Produktnummer ABIN1881139
  • Target Alle CASR Antikörper anzeigen
    CASR (Calcium-Sensing Receptor (CASR))
    Bindungsspezifität
    • 22
    • 20
    • 14
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-287
    Reaktivität
    • 86
    • 45
    • 38
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 86
    • 12
    Kaninchen
    Klonalität
    • 88
    • 10
    Polyklonal
    Konjugat
    • 45
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CASR Antikörper ist unkonjugiert
    Applikation
    • 79
    • 34
    • 23
    • 18
    • 18
    • 11
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, Pig, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CASR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-287 amino acids from the Central region of human CASR.
    Klon
    RB41198
    Isotyp
    IgG
    Top Product
    Discover our top product CASR Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • OSeaghdha, Yang, Glazer, Leak, Dehghan, Smith, Kao, Lohman, Hwang, Johnson, Hofman, Uitterlinden, Chen, Brown, Siscovick, Harris, Psaty, Coresh, Gudnason, Witteman, Liu, Kestenbaum, Fox, Köttgen: "Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels." in: Human molecular genetics, Vol. 19, Issue 21, pp. 4296-303, (2010) (PubMed).

    Giroux, Elfassihi, Clément, Bussières, Bureau, Cole, Rousseau: "High-density polymorphisms analysis of 23 candidate genes for association with bone mineral density." in: Bone, Vol. 47, Issue 5, pp. 975-81, (2010) (PubMed).

  • Target
    CASR (Calcium-Sensing Receptor (CASR))
    Andere Bezeichnung
    CASR (CASR Produkte)
    Hintergrund
    The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq].
    Molekulargewicht
    120675
    NCBI Accession
    NP_000379, NP_001171536
    UniProt
    P41180
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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