ATP6AP2 Antikörper (AA 205-234)

Produktnummer ABIN1881092

Produktdetails anti-ATP6AP2 Antikörper

Target: ATP6AP2 (ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))

Bindungsspezifität: AA 205-234

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6AP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6AP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human ATP6AP2.

Klon: RB41871

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ATP6AP2 Antikörper (ABIN1881092)

Takahashi, Yamamoto, Hirose, Hiraishi, Shoji, Shibasaki, Kato, Kaneko, Sasano, Satoh, Totsune: "Expression of (pro)renin receptor in human kidneys with end-stage kidney disease due to diabetic nephropathy." in: Peptides, Vol. 31, Issue 7, pp. 1405-8, (2010) (PubMed).

Cruciat, Ohkawara, Acebron, Karaulanov, Reinhard, Ingelfinger, Boutros, Niehrs: "Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling." in: Science (New York, N.Y.), Vol. 327, Issue 5964, pp. 459-63, (2010) (PubMed).

Nabi, Biswas, Nakagawa, Ichihara, Inagami, Suzuki: "Prorenin has high affinity multiple binding sites for (pro)renin receptor." in: Biochimica et biophysica acta, Vol. 1794, Issue 12, pp. 1838-47, (2009) (PubMed).

Alcazar, Cousins, Striker, Marin-Castano: "(Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling." in: Experimental eye research, Vol. 89, Issue 5, pp. 638-47, (2009) (PubMed).

Takemitsu, Ichihara, Kaneshiro, Sakoda, Kurauchi-Mito, Narita, Kinouchi, Yamashita, Itoh: "Association of (pro)renin receptor mRNA expression with angiotensin-converting enzyme mRNA expression in human artery." in: American journal of nephrology, Vol. 30, Issue 4, pp. 361-70, (2009) (PubMed).

Details zu ATP6AP2

Target: ATP6AP2 (ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))

Andere Bezeichnung: ATP6AP2 (ATP6AP2 Produkte)

Synonyme: APT6M8-9 antikoerper, ATP6IP2 antikoerper, ATP6M8-9 antikoerper, ELDF10 antikoerper, M8-9 antikoerper, MRXE antikoerper, MSTP009 antikoerper, XMRE antikoerper, (P)RR antikoerper, 5730403E06Rik antikoerper, Atp6ip2 antikoerper, tj6 antikoerper, wss antikoerper, arcl antikoerper, j6b7 antikoerper, stv1 antikoerper, tj6m antikoerper, tj6s antikoerper, vph1 antikoerper, atp6a2 antikoerper, atp6n1d antikoerper, ATP6AP2 antikoerper, DKFZp459G0918 antikoerper, atp6ap2 antikoerper, wu:fj36c03 antikoerper, wu:fq15e04 antikoerper, zgc:73194 antikoerper, ATPase H+ transporting accessory protein 2 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 2 antikoerper, ATPase H+ transporting V0 subunit d2 antikoerper, ATPase H+ transporting V0 subunit a2 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 2 S homeolog antikoerper, ATP6AP2 antikoerper, Atp6ap2 antikoerper, ATP6V0D2 antikoerper, atp6v0a2 antikoerper, atp6ap2.S antikoerper, atp6ap2 antikoerper

Hintergrund: This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

Molekulargewicht: 39008

NCBI Accession: NP_005756

UniProt: O75787

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones