RORA Antikörper (AA 164-401)

Produktnummer ABIN1860465

Produktdetails anti-RORA Antikörper

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Bindungsspezifität: AA 164-401

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Polyclonal Antibody to RAR Related Orphan Receptor Alpha (RORa)

Spezifität: The antibody is a rabbit polyclonal antibody raised against RORa. It has been selected for its ability to recognize RORa in immunohistochemical staining and western blotting.

Kreuzreaktivität: Maus

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant RAR Related Orphan Receptor Alpha (RORa) corresdonding to Gln164~Met401 with N-terminal His Tag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-2 μg/mL

1:500-2000 Immunohistochemistry: 5-20 μg/mL

1:50-200 Immunocytochemistry: 5-20 μg/mL

1:50-200 Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Referenzen für anti-RORA Antikörper (ABIN1860465)

Yasui, Matsuzaki, Konno, Hirai: "Global Knockdown of Retinoid-related Orphan Receptor α in Mature Purkinje Cells Reveals Aberrant Cerebellar Phenotypes of Spinocerebellar Ataxia." in: Neuroscience, (2020) (PubMed).

Details zu RORA

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Andere Bezeichnung: RAR Related Orphan Receptor Alpha (RORA Produkte)

Synonyme: ror1 antikoerper, ror2 antikoerper, ror3 antikoerper, rzra antikoerper, nr1f1 antikoerper, MGC146531 antikoerper, NR1F1 antikoerper, ROR1 antikoerper, ROR2 antikoerper, ROR3 antikoerper, RZR-ALPHA antikoerper, RZRA antikoerper, RORalpha-B antikoerper, gb:dq017624 antikoerper, rora2 antikoerper, 9530021D13Rik antikoerper, Nr1f1 antikoerper, nmf267 antikoerper, sg antikoerper, staggerer antikoerper, tmgc26 antikoerper, RORalpha1 antikoerper, RAR related orphan receptor A antikoerper, RAR-related orphan receptor A antikoerper, RAR-related orphan receptor A, paralog a antikoerper, RAR-related orphan receptor alpha antikoerper, RORA antikoerper, rora antikoerper, Rora antikoerper, roraa antikoerper

Hintergrund: ROR1, ROR2, NR1F1, ROR3, RZRA, Nuclear receptor subfamily 1 group F member 1, Retinoid-related orphan receptor-alpha

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha