LAG3 Antikörper (AA 244-487)

Produktnummer ABIN1859592

Produktdetails anti-LAG3 Antikörper

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Bindungsspezifität: AA 244-487

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Polyclonal Antibody to Lymphocyte Activation Gene 3 (LAG3)

Spezifität: The antibody is a rabbit polyclonal antibody raised against LAG3. It has been selected for its ability to recognize LAG3 in immunohistochemical staining and western blotting.

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Lymphocyte Activation Gene 3 (LAG3) corresdonding to Thr244~Glu487 with N-terminal His Tag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-2 μg/mL

1:330-1300 Immunohistochemistry: 5-20 μg/mL

1:33-130 Immunocytochemistry: 5-20 μg/mL

1:33-130 Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung: Lymphocyte Activation Gene 3 (LAG3 Produkte)

Synonyme: CD223 antikoerper, LAG-3 antikoerper, Ly66 antikoerper, lymphocyte activating 3 antikoerper, lymphocyte-activation gene 3 antikoerper, LAG3 antikoerper, Lag3 antikoerper

Hintergrund: CD223, Protein FDC

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints