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PAI1 Antikörper (Internal Region)

Verified SERPINE1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN185384
  • Target Alle PAI1 (SERPINE1) Antikörper anzeigen
    PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
    Bindungsspezifität
    • 15
    • 15
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 138
    • 38
    • 20
    • 12
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 109
    • 30
    • 7
    • 5
    • 1
    Ziege
    Klonalität
    • 121
    • 32
    Polyklonal
    Konjugat
    • 85
    • 17
    • 15
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser PAI1 Antikörper ist unkonjugiert
    Applikation
    • 112
    • 65
    • 47
    • 26
    • 26
    • 18
    • 16
    • 16
    • 13
    • 13
    • 9
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    PAI1 / SERPINE1
    Sequenz
    GFKIDDKGMA PALRH
    Kreuzreaktivität
    Hund, Human
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Immunogen
    Peptide with sequence C-GFKIDDKGMAPALRH, from the internal region of the protein sequence according to NP_000593.1, NP_001158885.1.
    Isotyp
    IgG
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  • Applikationshinweise

    Immunohistochemistry: In paraffin embedded Human Placenta shows strong staining of cytotrophoblasts. Recommended concentration: 4-6 μg/mL. A customer successfully used this product on Human Breast cancer.

    Western Blot: Approx 48 kDa band observed in Human Liver and HeLa lysates, while approx. 45 kDa observed in lyates of cell lines A549 and HepG2 (calculated MW of 45.1 kDa according to NP_000593.1). This molecular weight is routinely observed by other source

    Peptide ELISA: antibody detection limit dilution 1:64000.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Kozaczuk, Selmi, Bednarek: "Bacterial expression, purification and angiogenesis-promoting activity of human thymosin ?4." in: Protein expression and purification, Vol. 90, Issue 2, pp. 142-52, (2013) (PubMed).

  • Target
    PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
    Andere Bezeichnung
    SERPINE1 (SERPINE1 Produkte)
    Synonyme
    PAI antikoerper, PAI-1 antikoerper, PAI1 antikoerper, PLANH1 antikoerper, SERPINE1 antikoerper, si:ch211-138a11.1 antikoerper, Planh1 antikoerper, PAI1A antikoerper, Pai1 antikoerper, Pai1aa antikoerper, Planh antikoerper, RATPAI1A antikoerper, serpin family E member 1 antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade E, member 1 antikoerper, SERPINE1 antikoerper, serpine1.L antikoerper, serpine1 antikoerper, Serpine1 antikoerper
    Hintergrund
    SERPINE1, PAI1, PAI, PAI-1, PLANH1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, plasminogen activator inhibitor, type I, serpin peptidase inhibitor, clade E (nexin, plasminogen activator in
    Molekulargewicht
    45.1kDa
    Gen-ID
    5054
    NCBI Accession
    NP_000593
    Pathways
    p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration
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