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NPC1 Antikörper (AA 34-174)

NPC1 Reaktivität: Human ELISA, WB, IHC, FACS Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN1845969
  • Target Alle NPC1 Antikörper anzeigen
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    Bindungsspezifität
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 34-174
    Reaktivität
    • 47
    • 19
    • 14
    • 2
    Human
    Wirt
    • 42
    • 5
    • 2
    Maus
    Klonalität
    • 35
    • 14
    Monoklonal
    Konjugat
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NPC1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 27
    • 20
    • 15
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Aufreinigung
    Purified
    Immunogen
    Purified recombinant fragment of human NPC1 (AA: 34-174) expressed in E. coli.
    Isotyp
    IgG1
    Top Product
    Discover our top product NPC1 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20 °C.
  • Target
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    Andere Bezeichnung
    NPC1 (NPC1 Produkte)
    Synonyme
    NPC antikoerper, 9130221N23Rik antikoerper, Gm243 antikoerper, Cdig2 antikoerper, im:7149020 antikoerper, wu:fb53a12 antikoerper, wu:fc29a12 antikoerper, A430089E03Rik antikoerper, C85354 antikoerper, D18Ertd139e antikoerper, D18Ertd723e antikoerper, lcsd antikoerper, nmf164 antikoerper, spm antikoerper, NPC intracellular cholesterol transporter 1 antikoerper, NPC1 like intracellular cholesterol transporter 1 antikoerper, Niemann-Pick disease, type C1 antikoerper, Niemann-Pick C1 protein antikoerper, NPC1 antikoerper, Npc1l1 antikoerper, Npc1 antikoerper, npc1 antikoerper, LOC579887 antikoerper
    Hintergrund
    This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus.This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol.Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.
    Molekulargewicht
    142.2 kDa
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