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FAS Antikörper

FAS Reaktivität: Human WB, FACS, ELISA Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN1845671
  • Target Alle FAS Antikörper anzeigen
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Reaktivität
    • 227
    • 68
    • 66
    • 19
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 159
    • 102
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 156
    • 116
    • 1
    Monoklonal
    Konjugat
    • 131
    • 29
    • 25
    • 12
    • 11
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAS Antikörper ist unkonjugiert
    Applikation
    • 167
    • 131
    • 75
    • 68
    • 40
    • 36
    • 34
    • 26
    • 26
    • 20
    • 19
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human FAS expressed in E. coli.
    Isotyp
    IgG1
    Top Product
    Discover our top product FAS Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Andere Bezeichnung
    FAS (FAS Produkte)
    Synonyme
    ALPS1A antikoerper, APO-1 antikoerper, APT1 antikoerper, CD95 antikoerper, FAS1 antikoerper, FASTM antikoerper, TNFRSF6 antikoerper, AI196731 antikoerper, APO1 antikoerper, TNFR6 antikoerper, Tnfrsf6 antikoerper, lpr antikoerper, Fas cell surface death receptor antikoerper, Fas (TNF receptor superfamily member 6) antikoerper, FAS antikoerper, Fas antikoerper, fas antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the TNF-receptor superfamily.This receptor contains a death domain.It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10.The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis.This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells.Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD).The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
    Molekulargewicht
    37.7 kDa
    Gen-ID
    355
    UniProt
    P25445
    Pathways
    p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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