BAD Antikörper (pSer112)

Produktnummer ABIN1842343

Produktdetails anti-BAD Antikörper

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Bindungsspezifität: pSer112

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Rabbit Anti-BAD Polyclonal Antibody detects endogenous levels of total BAD protein.

Produktmerkmale: Molecular Weight: Predicted Band Size 23 kDa, Observed Band Size 23 kDa

Aufreinigung: The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from human BAD around pSer112 (H-S-SP-Y-P)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1,000,
IHC: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide, and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage.
Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for 1 year.

Referenzen für anti-BAD Antikörper (ABIN1842343)

Marchion, Cottrill, Xiong, Chen, Bicaku, Fulp, Bansal, Chon, Stickles, Kamath, Hakam, Li, Su, Moreno, Judson, Berchuck, Wenham, Apte, Gonzalez-Bosquet, Bloom, Eschrich, Sebti, Chen, Lancaster: "BAD phosphorylation determines ovarian cancer chemosensitivity and patient survival." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 19, pp. 6356-66, (2011) (PubMed).

Details zu BAD

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Andere Bezeichnung: BAD (BAD Produkte)

Synonyme: bad antikoerper, fa01b12 antikoerper, wu:fa01b12 antikoerper, wu:fa96d04 antikoerper, BAD antikoerper, BBC2 antikoerper, BCL2L8 antikoerper, AI325008 antikoerper, Bbc2 antikoerper, BCL2-associated agonist of cell death b antikoerper, BCL2 associated agonist of cell death antikoerper, BCL2-associated agonist of cell death antikoerper, badb antikoerper, BAD antikoerper, Bad antikoerper

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events