CD2-Associated Protein (Cd2ap) (AA 50-100) Antikörper

Details zu Produkt Nr. ABIN1842072
Antigen
Epitop
AA 50-100
5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Maus, Ratte (Rattus)
49
30
26
Wirt
Kaninchen
50
2
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
43
26
18
8
7
4
4
1
1
1
Optionen
Immunogen A synthetic peptide from aa region 50-100 of mouse CD2AP conjugated to an immunogenic carrier protein was used as the antigen.
Spezifität Specific for CD2AP.
Reinigung Whole serum
Antigen
Andere Bezeichnung CD2AP (Cd2ap Antibody Abstract)
Hintergrund FUNCTION: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. SUBCELLULAR LOCATION: Cytoplasm > cytoskeleton. Cell projection > ruffle. Note: Colocalizes with F-actin and BCAR1/p130Cas in membrane ruffles. Located at podocyte slit diaphragm between podocyte foot processes. During late anaphase and telophase, concentrates in the vicinity of the midzone microtubules and in the midbody in late telophase. Tissue specificity: Widely expressed in fetal and adult tissues.
Synonyms: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains
Applikations-hinweise A dilution of 1: 300 to 1: 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handhabung Avoid freeze and thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit 12 months