TNFRSF12A Antikörper (PE)

Produktnummer ABIN1819127

Produktdetails anti-TNFRSF12A Antikörper (PE)

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF12A Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266, see for details. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.

Aufreinigung: Protein G purified

Immunogen: Human CD266 transfected P815 cells.

Type of Immunogen: Cells

Klon: ITEM-4

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Flo, IHC, IHC-Fr, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze. Protect from light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze. Protect from light.

Details zu TNFRSF12A

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Andere Bezeichnung: TNFRSF12A / FN14 (TNFRSF12A Produkte)

Synonyme: CD266 antikoerper, FN14 antikoerper, TWEAKR antikoerper, AI255180 antikoerper, C87282 antikoerper, Fn14 antikoerper, HPIP antikoerper, TWEAK-R antikoerper, TweakR antikoerper, TNF receptor superfamily member 12A antikoerper, tumor necrosis factor receptor superfamily, member 12a antikoerper, TNFRSF12A antikoerper, Tnfrsf12a antikoerper

Hintergrund: Name/Gene ID: TNFRSF12A

Synonyms: TNFRSF12A, CD266 antigen, CD266, FGF-inducible 14, FN14, Tweak-receptor, TWEAKR

Gen-ID: 51330

Pathways: Apoptose, Regulation of Cell Size