GLUT4 Antikörper (AA 495-509)

Produktnummer ABIN1742482

Produktdetails anti-GLUT4 Antikörper

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Bindungsspezifität: AA 495-509

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for GLUT 4.

Aufreinigung: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide (aa 495-509 of human GLUT 4) coupled to KLH via an N-terminal added cysteine.

Anwendungsinformationen

Applikationshinweise: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not tested yet
IHC-P: 1 : 200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handhabung: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Lagerung: -20 °C

Informationen zur Lagerung: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Referenzen für anti-GLUT4 Antikörper (ABIN1742482)

Roccisana, Sadler, Bryant, Gould: "Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45." in: Molecular biology of the cell, Vol. 24, Issue 15, pp. 2389-97, (2013) (PubMed).

Boyle, Logan, Jones, Small, Sattar, Connell, Cleland, Salt: "AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study." in: Diabetologia, Vol. 54, Issue 7, pp. 1799-809, (2011) (PubMed).

Details zu GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Andere Bezeichnung: GLUT 4 (SLC2A4 Produkte)

Synonyme: GLUT4 antikoerper, Glut-4 antikoerper, Glut4 antikoerper, glut4 antikoerper, slc2a4 antikoerper, SLC2A4 antikoerper, solute carrier family 2 member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antikoerper, SLC2A4 antikoerper, Slc2a4 antikoerper, GLUT4 antikoerper, slc2a4.L antikoerper

Hintergrund: Synonyms: SLC2A4

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt