Abeta 1-40 Antikörper (AA 33-40)

Produktnummer ABIN1742443

Produktdetails anti-Abeta 1-40 Antikörper

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Bindungsspezifität: AA 33-40

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Abeta 1-40 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Spezifität: Specific for Abeta 40

Kreuzreaktivität (Details): no cross reactivity to Abeta 38 and 42.

Aufreinigung: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide corresponding to aa 33-40 of Abeta 40 coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Anwendungsinformationen

Applikationshinweise: WB: 1 : 1000
IP: not tested yet
ICC: not tested yet
IHC: 1 : 200 up to 1 : 500
IHC-P: 1 : 100 up to 1 : 500

Kommentare:

WB: Detects purified Abeta 40. Complex samples like brain extracts still have to be tested. ELISA: suitable as capture and detector antibody for sandwich-ELISA (protocol for sandwich-ELISA).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handhabung: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Lagerung: -20 °C

Informationen zur Lagerung: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Referenzen für anti-Abeta 1-40 Antikörper (ABIN1742443)

Christensen, Huettenrauch, Mitkovski, Pradier, Wirths: "Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal A? accumulation." in: Frontiers in aging neuroscience, Vol. 6, pp. 139, (2014) (PubMed).

Details zu Abeta 1-40

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Andere Bezeichnung: Abeta 40 (Abeta 1-40 Produkte)

Synonyme: AAA antikoerper, ABETA antikoerper, ABPP antikoerper, AD1 antikoerper, APPI antikoerper, CTFgamma antikoerper, CVAP antikoerper, PN-II antikoerper, PN2 antikoerper, amyloid beta precursor protein antikoerper, APP antikoerper

Hintergrund: Synonyms: Beta-App, ABPP